Chemical and Biological Systems Optimization Lab.

Thank you for visiting the Chemical & Biological Systems Optimization Lab at Penn State.

The group is led by Dr. Costas D. Maranas, Donald B. Broughton Professor of the Department of Chemical Engineering. Research interests include metabolic network reconstruction, analysis and redesign; synthetic biology and microbial strain design for bio-production; computational protein, enzyme and antibody design; and bioinformatics.

The C. Maranas lab (http://maranas.che.psu.edu) has a number of research openings for PSU undergraduate students. Research funding is available for work during the academic year and summer semester. Exceptional candidates have in the past been admitted into the graduate program receiving full graduate student stipends beginning the Summer (or even Spring) semester of their senior year. One project track involves metabolic model construction and computational strain redesign for the production of bio-renewables and biofuels. Emphasis will be placed on organisms that can make use of unconventional carbon sources (e.g., methane, carbon dioxide, etc.). The second track involves the development of computational tools for the computer-aided design of proteins, antibodies and enzymes. Depending on the project, students will be expected to develop a strong biochemistry or biophysics background, good programming skills and knowledge of systems optimization. All projects will be carried out in collaboration with leading experimental labs in the US with possible student exchange opportunities. Early participation in scientific conferences and opportunities for research presentations will be made available. You should contact Prof. Costas D. Maranas at costas@psu.edu for additional information.

You can learn more about our group's research, or download our journal publications.


Photo of the entire Costas Maranas Research Group from July 2013.
Meet the group members!

International Genetically Engineered Machines logo.
Maranas lab from Chemical Engineering in collaboration with Wash U's iGEM (International Genetically Engineered Machines) team is recruiting self-motivated undergraduate students from all backgrounds to participate in the research this summer!


Contact Information:
Costas D. Maranas' office:
112 Fenske Laboratory
University Park, PA 16802
email: costas@psu.edu
phone: 814.863.9958
fax: 814.865.7846

Group offices:
147A Fenske Lab – 814.863.1689
147B Fenske Lab – 814.863.3385
149 Fenske Lab – 814.863.4806

November 2014 - Nathan Esperon a graduate student in Chemical Engineering joined Maranas’ group. Welcome!

September 2014 - Chiam Yu Ng won the Best Presentation award in Synberc 2014 Fall Retreat. Congratulations!

August 2014 - Saratram Gopalakrishnan won the Best Candidacy Exam Award. Congratulations!

June 2014 - Rajib Saha successfully defended his PhD, Congratulations!

April 2014 - Hadi Nazem-Bokaee joined Maranas' group as a postdoc. Welcome!

February 2014 - Mohammad Mazharul Islam successfully defended his Masters thesis and will be continuing as a PhD student. Congratulations!

January 2014 - Robert Pantazes successfully defended his PhD, Congratulations!

October 2013 - Sarat Gopalakrishnan and Ratul Chowdhury, graduate students in Chemical Engineering, joined Maranas' group. Welcome!

September 2013 - Review paper co-authored by Rajib Saha was highlighted on the Frontiers homepage. Congratulations!

August 2013 - Chiam Yu Ng won the Best Candidacy Exam Award. Congratulations!

August 2013 - Satyakam Dash joined Maranas’ group as a graduate research assistant. Welcome!

April 2013 - Matt Grisewood successfully defended his Masters thesis and will be continuing as a PhD student. Congratulations!

January 2013 - Tom Mueller a graduate student in Chemical Engineering joined Maranas’ group. Welcome!

October 2012 - Chiam Yu Ng, Mohammad Islam, and Margaret Simons, first year graduate students in Chemical Engineering joined Maranas’ group. Welcome!

May 2012 - Ali Zomorrodi successfully defended his PhD, Congratulations!

April 2012 - Anupam Chowdhury receives the Leighton Riess Graduate Fellowship, Way to go Anupam!

February 2012 - Ali Khodayari a first year graduate student in Chemical Engineering joined Maranas' group, Welcome!


www.metrxn.che.psu.edu Useful Links. Publications.